Complete Record - Heirs of Hippocrates No. 2156

PAUL EHRLICH (1854-1915) Das Sauerstoff-Bedürfniss des Organismus. August Hirschwald 1885 [4] 167 pp. 22.1 cm.

Ehrlich, director of the Institute for Serum Research and Serum Testing at Frankfurt for many years, made many key contributions to immunology, chemotherapy, and hematology. His original and wide-ranging research had much to do with modern knowledge of the biological processes that occur within the cell and it was his work that laid the foundation for chemotherapy. At the time he wrote the present work he was head physician in Frerichs' (see No. 1877) clinic at the Charité in Berlin. It was in this book that he reported on his use of the dyes alizarin blue and indophenol blue to study the manner in which oxygen was used by living tissues. Ehrlich found that tissues consume oxygen at varying rates and that cellular processes could be measured by determining the amount of oxidation. From this important work he went on to develop his side-chain theory which specified that certain receptors on the cell surface could combine with and assimilate nutrients as well as toxic substances.

See Related Record(s): 1877

Cited references: Garrison-Morton 2540; Waller 2705

Gift of John Martin, M.D.